Primary structure and functional expression of a cyclic nucleotidegated channel from rabbit aorta
Episode von Chemie und Pharmazie - Open Access LMU - Teil 02/02 von Ludwig-Maximilians-Universität München · 1. Januar 1993
Sequences specific for cyclic nucleotide-gated channels (CNG channels) have been amplified by PCR from cDNA of heart, aorta, sinoatrial node, cerebellum, C-cells and kidney. The complete amino acid sequence of a CNG channel from rabbit aorta has been deduced by cloning and sequence analysis of the cDNA. Synthetic RNA derived from this cDNA induces the formation of a functional CNG channel in Xenopus oocytes.
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