Medizin - Open Access LMU - Teil 22/22

von Ludwig-Maximilians-Universität München · Bildung

Die Universitätsbibliothek (UB) verfügt über ein umfangreiches Archiv an elektronischen Medien, das von Volltextsammlungen über Zeitungsarchive, Wörterbücher und Enzyklopädien bis hin zu ausführlichen Bibliographien und mehr als 1000 Datenbanken reicht. Auf iTunes U stellt die UB unter anderem eine Auswahl an elektronischen Publikationen der Wissenschaftlerinnen und Wissenschaftler an der LMU bereit. (Dies ist der 22. von 22 Teilen der Sammlung 'Medizin - Open Access LMU'.)

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A comprehensive analysis of Helicobacter pylori plasticity zones reveals that they are integrating conjugative elements with intermediate integration specificity
1. Januar 2014
Background: The human gastric pathogen Helicobacter pylori is a paradigm for chronic bacterial infections. Its persistence in the stomach mucosa is facilitated by several…
A cross-sectional analysis of the effects of residential greenness on blood pressure in 10-year old children: results from the GINIplus and LISAplus studies
1. Januar 2014
Background: According to Ulrich's psychoevolutionary theory, contact with green environments mitigates stress by activating the parasympathetic system, (specifically, by…
A large kindred of pulmonary fibrosis associated with a novel ABCA3 gene variant
1. Januar 2014
Background: Interstitial lung disease occurring in children is a condition characterized by high frequency of cases due to genetic aberrations of pulmonary surfactant…
A randomised multicentre trial of acupuncture in patients with seasonal allergic rhinitis - trial intervention including physician and treatment characteristics
1. Januar 2014
Background: In a large randomised trial in patients with seasonal allergic rhinitis (SAR), acupuncture was superior compared to sham acupuncture and rescue medication. The aim of…
Association between anemia and falls in community-dwelling older people: cross-sectional results from the KORA-Age study
1. Januar 2014
Background: Falls and fractures are among the principal causes of disability, and mortality of older people. Therefore, identifying treatable risk factors for falls in this…
Biological health or lived health: which predicts self-reported general health better?
1. Januar 2014
Background: Lived health is a person's level of functioning in his or her current environment and depends both on the person's environment and biological health. Our study…
Circulating cell-free methylated DNA and lactate dehydrogenase release in colorectal cancer
1. Januar 2014
Background: Hypermethylation of DNA is an epigenetic alteration commonly found in colorectal cancer (CRC) and can also be detected in blood samples of cancer patients.…
Comparative cost-effectiveness analyses of cardiovascular magnetic resonance and coronary angiography combined with fractional flow reserve for the diagnosis of coronary artery disease
1. Januar 2014
Background: According to recent guidelines, patients with coronary artery disease (CAD) should undergo revascularization if significant myocardial ischemia is present. Both,…
Comprehensive analysis of beta-catenin target genes in colorectal carcinoma cell lines with deregulated Wnt/beta-catenin signaling
1. Januar 2014
Background: Deregulation of Wnt/beta-catenin signaling is a hallmark of the majority of sporadic forms of colorectal cancer and results in increased stability of the protein…
Contribution of socioeconomic status, stature and birth weight to obesity in Sub-Saharan Africa: cross-sectional data from primary school-age children in Cameroon
1. Januar 2014
Background: The pattern of obesity in relation to socioeconomic status is of public health concern. This study investigates whether the association between height and obesity in…
Early versus later response to treatment in patients with community-acquired pneumonia: analysis of the REACH study
1. Januar 2014
Background: Key goals in the treatment of CAP include early response to treatment and achievement of clinical stability. The US FDA recommends early response endpoints (72 hours…
Evidence-based decision-making in infectious diseases epidemiology, prevention and control: matching research questions to study designs and quality appraisal tools
1. Januar 2014
Background: The Project on a Framework for Rating Evidence in Public Health (PRECEPT) was initiated and is being funded by the European Centre for Disease Prevention and Control…
Evidence for significant influence of host immunity on changes in differential blood count during malaria
1. Januar 2014
Background: Malaria has been shown to change blood counts. Recently, a few studies have investigated the alteration of the peripheral blood monocyte-to-lymphocyte count ratio…
Experience of gratitude, awe and beauty in life among patients with multiple sclerosis and psychiatric disorders
1. Januar 2014
Background: Feelings of gratitude and awe facilitate perceptions and cognitions that go beyond the focus of illness and include positive aspects of one's personal and…
Exploring patterns of accelerometry-assessed physical activity in elderly people
1. Januar 2014
Background: Elderly people obtain significant health benefits from physical activity (PA), but the role of activity patterns has scarcely been researched. The present study aims…
FemZone trial: a randomized phase II trial comparing neoadjuvant letrozole and zoledronic acid with letrozole in primary breast cancer patients
1. Januar 2014
Background: The objective of this prospectively randomized phase II trial (Trial registration: EUCTR2004-004007-37-DE) was to compare the clinical response of primary breast…
Focal subarachnoid haemorrhage mimicking transient ischaemic attack - do we really need MRI in the acute stage?
1. Januar 2014
Background: Acute non-traumatic focal subarachnoid haemorrhage (fSAH) is a rare transient ischaemic attack (TIA)-mimic. MRI is considered to be indispensable by some authors in…
Genetic targeting of B-Raf(V600E) affects survival and proliferation and identifies selective agents against BRAF-mutant colorectal cancer cells
1. Januar 2014
Background: Colorectal cancers carrying the B-Raf V600E-mutation are associated with a poor prognosis. The purpose of this study was to identify B-Raf(V600E)-mediated traits of…
Good guy or bad guy: the opposing roles of microRNA 125b in cancer
1. Januar 2014
MicroRNAs (miRNAs) are a class of non-coding RNAs that post-transcriptionally silence target mRNAs. Dysregulation of miRNAs is a frequent event in several diseases, including…
International prevalence of adverse drug events in hospitals: an analysis of routine data from England, Germany, and the USA
1. Januar 2014
Background: Adverse drug events (ADEs) are frequent in hospitals, occurring either in patients before admission or as a nosocomial event, and either as a drug reaction or as a…
Interrogating causal pathways linking genetic variants, small molecule metabolites, and circulating lipids
1. Januar 2014
Background: Emerging technologies based on mass spectrometry or nuclear magnetic resonance enable the monitoring of hundreds of small metabolites from tissues or body fluids.…
Introduction to glycopathology: the concept, the tools and the perspectives
1. Januar 2014
Analyzing the flow of biological information is a fundamental challenge for basic sciences. The emerging results will then lend themselves to the development of new approaches…
Large-scale mitochondrial DNA analysis in Southeast Asia reveals evolutionary effects of cultural isolation in the multi-ethnic population of Myanmar
1. Januar 2014
Background: Myanmar is the largest country in mainland Southeast Asia with a population of 55 million people subdivided into more than 100 ethnic groups. Ruled by changing…
Microvascular dysfunction in the course of metabolic syndrome induced by high-fat diet
1. Januar 2014
Background: Metabolic syndrome (MetS) is associated with increased risk of cardiovascular disease (CVD). One important feature underlying the pathophysiology of many types of CVD…
Neural correlates of moral judgments in first- and third-person perspectives: implications for neuroethics and beyond
1. Januar 2014
Background: There appears to be an inconsistency in experimental paradigms used in fMRI research on moral judgments. As stimuli, moral dilemmas or moral statements/ pictures that…
Neuropathology of the posteroinferior occipitotemporal gyrus in children with autism
1. Januar 2014
Background: While most neuropathologic studies focus on regions involved in behavioral abnormalities in autism, it is also important to identify whether areas that appear…
NO, via its target Cx37, modulates calcium signal propagation selectively at myoendothelial gap junctions
1. Januar 2014
Background: Gap junctional calcium signal propagation (transfer of calcium or a calcium releasing messenger via gap junctions) between vascular cells has been shown to be…
Non-healing old world cutaneous leishmaniasis caused by L. infantum in a patient from Spain
1. Januar 2014
Background: The prevalence of Old World Cutaneous Leishmaniasis in the Mediterranean region is increasing and in Southern Europe often caused by Leishmania infantum. Spontaneous…
Phage idiotype vaccination: first phase I/II clinical trial in patients with multiple myeloma
1. Januar 2014
Background: Multiple myeloma is characterized by clonal expansion of B cells producing monoclonal immunoglobulins or fragments thereof, which can be detected in the serum and/or…
PLA1A2 platelet polymorphism predicts mortality in prediabetic subjects of the population based KORA S4-Cohort
1. Januar 2014
Objective: The genetic polymorphism concerning the beta 3-subunit of platelet integrin receptor glycoprotein IIIa is held responsible for enhanced binding of adhesive proteins…
Post-processing sets of tilted CT volumes as a method for metal artifact reduction
1. Januar 2014
Background: Metal implants, surgical clips and other foreign bodies may cause `streaking' or `star' artifacts in computed tomography (CT) reconstructions, for example in the…
Prevalence of asthma, rhinitis and eczema symptoms in rural and urban school-aged children from Oropeza Province - Bolivia: a cross-sectional study
1. Januar 2014
Background: Asthma and allergies are world-wide common chronic diseases among children and young people. Little information is available about the prevalence of these diseases in…
Prognostic factors for survival and radiation necrosis after stereotactic radiosurgery alone or in combination with whole brain radiation therapy for 1-3 cerebral metastases
1. Januar 2014
Background: In the present study factors affecting survival and toxicity in cerebral metastasized patients treated with stereotactic radiosurgery (SRS) were analyzed with special…
Promoting medical competencies through international exchange programs: benefits on communication and effective doctor-patient relationships
1. Januar 2014
Background: Universities are increasingly organizing international exchange programs to meet the requirements of growing globalisation in the field of health care. Analyses based…
Public stigma against family members of people with mental illness: findings from the Gilgel Gibe Field Research Center (GGFRC), Southwest Ethiopia
1. Januar 2014
Background: Public stigma against family members of people with mental illness is a negative attitude by the public which blame family members for the mental illness of their…
Radiation-induced alterations of histone post-translational modification levels in lymphoblastoid cell lines
1. Januar 2014
Background: Radiation-induced alterations in posttranslational histone modifications (PTMs) may affect the cellular response to radiation damage in the DNA. If not reverted…
Release of monocyte migration signals by breast cancer cell lines after ablative and fractionated gamma-irradiation
1. Januar 2014
Background: Radiotherapy, administered in fractionated as well as ablative settings, is an essential treatment component for breast cancer. Besides the direct tumor cell death…
Reproductive factors, intima media thickness and carotid plaques in a cross-sectional study of postmenopausal women enrolled in the population-based KORA F4 study
1. Januar 2014
Background: Reproductive events may affect the onset of chronic diseases. We examined the possible association between reproductive parameters and intima media thickness (IMT) or…
Resource use by patients hospitalized with community-acquired pneumonia in Europe: analysis of the REACH study
1. Januar 2014
Background: Management of community-acquired pneumonia (CAP) places a considerable burden on hospital resources. REACH was a retrospective, observational study (NCT01293435)…
Risk of contralateral second primary breast cancer according to hormone receptor status in Germany
1. Januar 2014
Introduction: Hormone receptor (HR) status has become an established target in treatment strategies of breast cancer. Population-based estimates of contralateral breast cancer…

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Die neueste Episode „A comprehensive analysis of Helicobacter pylori plasticity zones reveals that they are integrating conjugative elements with intermediate integration specificity“ erschien am 1. Januar 2014.

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