Medizin - Open Access LMU - Teil 15/22
von Ludwig-Maximilians-Universität München · Bildung
Die Universitätsbibliothek (UB) verfügt über ein umfangreiches Archiv an elektronischen Medien, das von Volltextsammlungen über Zeitungsarchive, Wörterbücher und Enzyklopädien bis hin zu ausführlichen Bibliographien und mehr als 1000 Datenbanken reicht. Auf iTunes U stellt die UB unter anderem eine Auswahl an elektronischen Publikationen der Wissenschaftlerinnen und Wissenschaftler an der LMU bereit. (Dies ist der 15. von 22 Teilen der Sammlung 'Medizin - Open Access LMU'.)
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Episoden
- An in vivo evaluation of Brilliant Blue G in animals and humans
1. Januar 2008
Background/Aims: To evaluate the retinal toxicity of Brilliant Blue G (BBG) following intravitreal injection in rat eyes and examine the biocompatibility and the staining… - Retention of mouth-to-mouth, mouth-to-mask and mouth-to-face shield ventilation
1. Januar 2008
Background: Retention of mouth-to-mouth, mouth-to-mask and mouth-to-face shield ventilation techniques is poorly understood.Methods: A prospective randomised clinical trial was… - Occupation and adult onset of rhinitis in the general population
1. Januar 2008
Objectives: Occupational exposures have been associated with an increased risk of new-onset rhinitis in apprentices. However, population-based prospective data are scarce and do… - Syk-mediated translocation of PI3Kδ to the leading edge controls lamellipodium formation and migration of leukocytes
7. November 2007
The non-receptor tyrosine kinase Syk is mainly expressed in the hematopoietic system and plays an essential role in β2 integrin-mediated leukocyte activation. To elucidate the… - Evolutionary aspects in evaluating mutations in the melanocortin 4 receptor
1. Oktober 2007
More than 70 missense mutations have been identified in the human melanocortin 4 receptor (MC4R), and many of them have been associated with obesity. In a number of cases, the… - Natural killer cells promote early CD8 T cell responses against cytomegalovirus.
24. August 2007
Understanding the mechanisms that help promote protective immune responses to pathogens is a major challenge in biomedical research and an important goal for the design of… - Analysis of intraviral protein-protein interactions of the SARS coronavirus ORFeome
23. Mai 2007
The severe acute respiratory syndrome coronavirus (SARS-CoV) genome is predicted to encode 14 functional open reading frames, leading to the expression of up to 30 structural and… - The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts
1. April 2007
A SNP upstream of the INSIG2 gene, rs7566605, was recently found to be associated with obesity as measured by body mass index (BMI) by Herbert and colleagues. The association… - Absence of Ret signaling in mice causes progressive and late degeneration of the nigrostriatal system
1. März 2007
Support of ageing neurons by endogenous neurotrophic factors such as glial cell line-derived neurotrophic factor (GDNF) and brain-derived neurotrophic factor (BDNF) may determine… - Does respiratory health contribute to the effects of long-term air pollution exposure on cardiovascular mortality?
1. Januar 2007
Background: There is growing epidemiological evidence that short-term and long-term exposure to high levels of air pollution may increase cardiovascular morbidity and mortality.… - Effect of the angiotensin receptor blocker irbesartan on metabolic parameters in clinical practice: the DO-IT prospective observational study
1. Januar 2007
Aims: A number of intervention studies have shown that therapy with angiotensin receptor blockers, such as irbesartan, can improve metabolic parameters and reduce the incidence… - Evidence for placebo effects on physical but not on biochemical outcome parameters: a review of clinical trials
1. Januar 2007
Background: Recent reviews on placebo effects in clinical trials suggest that objective changes following placebo treatments may not exist or, at least, have been considerably… - Gene transfer of wild-type apoA-I and apoA-I Milano reduce atherosclerosis to a similar extent
1. Januar 2007
Background: The atheroprotective effects of systemic delivery of either apolipoprotein A-I (wtApoA-I) or the naturally occurring mutant ApoA-I Milano (ApoA-I(M)) have been… - Generation of clinical grade dendritic cells with capacity to produce biologically active IL-12p70
1. Januar 2007
Background: For optimal T cell activation it is desirable that dendritic cells (DCs) display peptides within MHC molecules as signal 1, costimulatory molecules as signal 2 and,… - Health-related quality of life and long-term prognosis in chronic hypercapnic respiratory failure: a prospective survival analysis
1. Januar 2007
Background: Health-related quality of life (HRQL) is considered as an important outcome parameter in patients with chronic diseases. This study aimed to assess the role of… - In-vivo kinetics of inhaled 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in bronchial tissue
1. Januar 2007
Background: In the diagnosis of early-stage lung cancer photosensitizer-enhanced fluorescence bronchoscopy with inhaled 5-aminolevolinic acid ( 5-ALA) increases sensitivity when… - Influence of degree correlations on network structure and stability in protein-protein interaction networks
1. Januar 2007
Background: The existence of negative correlations between degrees of interacting proteins is being discussed since such negative degree correlations were found for the… - Intrahepatic cholestasis of pregnancy
1. Januar 2007
Intrahepatic cholestasis of pregnancy (ICP) is a cholestatic disorder characterized by (i) pruritus with onset in the second or third trimester of pregnancy, (ii) elevated serum… - Large-scale mapping of mutations affecting zebrafish development
1. Januar 2007
Background: Large-scale mutagenesis screens in the zebrafish employing the mutagen ENU have isolated several hundred mutant loci that represent putative developmental control… - Learning causal networks from systems biology time course data: an effective model selection procedure for the vector autoregressive process
1. Januar 2007
Background: Causal networks based on the vector autoregressive (VAR) process are a promising statistical tool for modeling regulatory interactions in a cell. However, learning… - Marker tolerant, immunocompetent animals as a new tool for regenerative medicine and long-term cell tracking
1. Januar 2007
Background: Immune- mediated rejection of labeled cells is a general problem in transplantation studies using cells labeled with any immunogenic marker, and also in gene therapy… - Meaning in life in the federal Republic of Germany: results of a representative survey with the Schedule for Meaning in Life Evaluation (SMiLE)
1. Januar 2007
Background: The construct "meaning- in- life" (MiL) has recently raised the interest of clinicians working in psycho-oncology and end-of-life care and has become a topic of… - Molecular surveillance of drug-resistance associated mutations of Plasmodium falciparum in south-west Tanzania
1. Januar 2007
Background: In Tanzania, drug-resistant malaria parasites are an increasing public health concern. Because of widespread chloroquine (CQ) resistance Tanzania changed its first… - Paternal smoking is associated with a decreased prevalence of type 1 diabetes mellitus among offspring in two national British birth cohort studies (NCDS and BCS70)
1. Januar 2007
Aims: An association between paternal age and type 1 diabetes (IDDM) among their offspring was recent reported as well as transgenerational responses in humans. This paper aims… - Pitfalls in measuring the endocannabinoid 2-arachidonoyl glycerol in biological samples
1. Januar 2007
Background: The endocannabinoid 2-arachidonoyl glycerol (2-AG) undergoes spontaneous isomerization to biologically inactive 1-AG. This effect has not been adequately addressed in… - Placental transfer of long-chain polyunsaturated fatty acids (LC-PUFA)
1. Januar 2007
Considerable evidence exists for marked beneficial effects of omega-3 long-chain polyunsaturated fatty acids (LC-PUFA) during pregnancy. The omega-3 LCPUFA docosahexaenoic acid… - Quantitative comparison of DNA detection by GFP-lac repressor tagging, fluorescence in situ hybridization and immunostaining
1. Januar 2007
Background: GFP-fusion proteins and immunostaining are methods broadly applied to investigate the three-dimensional organization of cells and cell nuclei, the latter often… - Spleen tyrosine kinase Syk is critical for sustained leukocyte adhesion during inflammation in vivo
1. Januar 2007
Background: During inflammation, beta(2)-integrins mediate leukocyte adhesion to the endothelium accompanied by the activation of the spleen tyrosine kinase Syk. Results: We… - Therapeutic T cells induce tumor-directed chemotaxis of innate immune cells through tumor-specific secretion of chemokines and stimulation of B16BL6 melanoma to secrete chemokines
1. Januar 2007
Background: The mechanisms by which tumor-specific T cells induce regression of established metastases are not fully characterized. In using the poorly immunogenic B16BL6-D5 (D5)… - Tumor-specific T cells signal tumor destruction via the lymphotoxin beta receptor
1. Januar 2007
Background: Previously, we reported that adoptively transferred perforin k/o (PKO), and IFN-gamma\k/o (GKO), or perforin/IFN-gamma double k/o (PKO/GKO) effector T cells mediated… - Acute and long-term survival in chronically critically ill surgical patients: a retrospective observational study
1. Januar 2007
Introduction Various cohort studies have shown that acute ( short-term) mortality rates in unselected critically ill patients may have improved during the past 15 years. Whether… - Acute childhood diarrhoea in northern Ghana: epidemiological, clinical and microbiological characteristics
1. Januar 2007
Background: Acute diarrhoea is a major cause of childhood morbidity and mortality in sub-Saharan Africa. Its microbiological causes and clinico-epidemiological aspects were… - Adjuvant therapeutic vaccination in patients with non-small cell lung cancer made lymphopenic and reconstituted with autologous PBMC: first clinical experience and evidence of an immune response
1. Januar 2007
Background: Given the considerable toxicity and modest benefit of adjuvant chemotherapy for non-small cell lung cancer (NSCLC), there is clearly a need for new treatment… - Antithrombin and hypercoagulability in sepsis: insights from thrombelastography?
1. Januar 2007
Antithrombin (AT) has been used for over 25 years to successfully treat disseminated intravascular coagulation (DIC). A four-day AT therapy in patients with DIC in the KyberSept… - Bias in random forest variable importance measures: Illustrations, sources and a solution
1. Januar 2007
Background: Variable importance measures for random forests have been receiving increased attention as a means of variable selection in many classification tasks in… - Bonding of articular cartilage using a combination of biochemical degradation and surface cross-linking
1. Januar 2007
After trauma, articular cartilage often does not heal due to incomplete bonding of the fractured surfaces. In this study we investigated the ability of chemical cross-linkers to… - Causes of metabolic acidosis in canine hemorrhagic shock: role of unmeasured ions
1. Januar 2007
Introduction Metabolic acidosis during hemorrhagic shock is common and conventionally considered to be due to hyperlactatemia. There is increasing awareness, however, that other… - Deleted in Malignant Brain Tumors 1 (DMBT1) is present in hyaline membranes and modulates surface tension of surfactant
1. Januar 2007
Background: Deleted in Malignant Brain Tumors 1 (DMBT1) is a secreted scavenger receptor cysteine-rich protein that binds various bacteria and is thought to participate in innate…
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Die Universitätsbibliothek (UB) verfügt über ein umfangreiches Archiv an elektronischen Medien, das von Volltextsammlungen über Zeitungsarchive, Wörterbücher und Enzyklopädien bis hin zu ausführlichen Bibliographien und mehr als 1000 Datenbanken reicht. Auf iTunes U stellt die UB unter anderem eine Auswahl an elektronischen Publikationen der Wissenschaftlerinnen und Wissenschaftler an der LMU bereit. (Dies ist der 15. von 22 Teilen der Sammlung 'Medizin - Open Access LMU'.)
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Aktuell sind 38 Episoden verfügbar.
Wann erschien die letzte Episode von „Medizin - Open Access LMU - Teil 15/22“?
Die neueste Episode „An in vivo evaluation of Brilliant Blue G in animals and humans“ erschien am 1. Januar 2008.